Assessment of the spread of tuberculosis infection among patients with HIV infection who were under the observation of phthisiatricians in the city of Moscow

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Observational analysis highlights tuberculosis incidence reduction in HIV patients undergoing preventive therapy.

Preventive therapy significantly lowers tuberculosis incidence in HIV patients, potentially reducing risk by nearly 50%.
Latent tuberculosis infection was found in an average of 4.6% of patients during their first visit, with variation across years.
Patients with CD4+ levels below 350 cells/ml saw a 3.5 times decrease in tuberculosis risk with effective preventive therapy.
The absence of complete preventive therapy greatly increased tuberculosis development risk in HIV patients with latent infection.

Bogorodskaya et al. (2025) studied this question.

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View Full Paper

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Observational analysis highlights tuberculosis incidence reduction in HIV patients undergoing preventive therapy.

Preventive therapy significantly lowers tuberculosis incidence in HIV patients, potentially reducing risk by nearly 50%.
Latent tuberculosis infection was found in an average of 4.6% of patients during their first visit, with variation across years.
Patients with CD4+ levels below 350 cells/ml saw a 3.5 times decrease in tuberculosis risk with effective preventive therapy.
The absence of complete preventive therapy greatly increased tuberculosis development risk in HIV patients with latent infection.

Bogorodskaya et al. (2025) studied this question.

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