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September 10, 2025International Journal of Infectious DiseasesOpen Access

Causative Pathogens and Predictors of Unfavourable Outcomes in Central Nervous System Infections in Resource-Limited Settings

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Authors

DDDo Van DongVSVu Viet SangNHNghiêm Xuân Hoàn

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Overview

Observational analysis assesses causative pathogens and predictors of unfavourable outcomes in CNS infections, suggesting targeted therapeutic approaches.

Key Points

  • Unfavourable outcomes were observed in 57% of patients with CNS infections, highlighting serious health risks.
  • Pathogens were identified in 24% of 330 patients, with Mycobacterium tuberculosis as the most significant contributor.
  • Multivariate analysis identified altered mental status on admission as a predictor for unfavourable outcomes.
  • Timely administration of appropriate empirical therapy significantly reduced the risk of mortality in these patients.

Cite This Study

Dong et al. (2025) studied this question.

synapsesocial.com/papers/68c2404eb210217d6479a183https://doi.org/10.1016/j.ijid.2025.108002
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Also Consider

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  1. 1Predictors of Mortality in CNS Tuberculosis: Clinical and Radiological Parameters2025
  2. 2Neuroimaging for prognosis of central nervous system infections: a systematic review and meta-analysis2025
  3. 3Antimicrobial Resistance and Microbiological Gap Analysis for Central Nervous System Infections Bacterial Pathogens in Nigeria2025
  4. 4Clinical and Laboratory Predictors of Poor Neurological Outcomes Following Infectious Encephalitis: Systematic Review and Meta‐Analysis2025
  5. 5CLINICAL AND DEMOGRAPHIC PROFILE OF INFECTIVE MENINGITIS IN A TERTIARY CARE CENTER: A CROSS-SECTIONAL STUDY2025