Successful collaborative management of a huge pseudotumour in a Haemophilia A patient living with HIV at North Okkalapa General Hospital: A Case Report

"Haemophilia is a rare X-linked congenital bleeding disorder characterized by a deficiency of coagulation factor VIII (FVIII), called haemophilia A, or factor IX (FIX), called haemophilia B. The factor deficiencies are the result of pathogenic variants in the F8 and F9 clotting factor genes. In Myanmar, the expected number of people with haemophilia is up to over 5,000 people but only over 800 people were reported. A 56-year-old man presented to Clinical Haematology Department of North Okkalapa General Hospital with a huge swelling at right proximal thigh. He first experienced excessive gum bleeding after tooth extraction at the age of 18 years, which was treated by blood transfusion, but he was not diagnosed to have bleeding disorder at that time. Fluctuations in clot factor levels during the first postoperative year may increase the likelihood of bleed recurrence. Therefore, close monitoring and optimal correction of clot factor levels are of paramount importance. Prevention of muscular haematoma in haemophilia patients is the key to reducing the incidence of pseudotumours."