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September 10, 2025PLoS ONEOpen Access

Association between oxidative balance score and systemic immune-inflammation index: NHANES 2003–2018

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Authors

YNYinghua NiuZFZiyi FanZWZelin Wang

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Overview

Observational analysis shows a negative link between oxidative balance score and systemic immune-inflammation index, indicating lifestyle may reduce inflammation.

Key Points

  • Higher oxidative balance scores have a significantly negative association with systemic immune-inflammation index.
  • In the top quartile, a β of -51.52 shows a strong link between antioxidant capacity and inflammation levels.
  • Multivariable linear regression and subgroup analyses were used to explore the relationship between scores and indices.
  • Improving antioxidant status through diet and lifestyle changes may effectively reduce systemic inflammation.

Cite This Study

Niu et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d64795a9fhttps://doi.org/10.1371/journal.pone.0329540
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