Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
September 10, 2025Frontiers in Cardiovascular MedicineOpen Access

The role of oxidative stress in modulating mortality risk across the hypertension control cascade

View Full Paper
Ask AI
Bookmark
Share

Authors

WLWeihao LiuCHChunyang HouHWHongjie Wang

Discussion

Loading...

Member takes

Overview

Cohort study shows lower mortality in hypertensive adults with high oxidative balance scores, suggesting mediation by inflammation.

Key Points

  • Higher oxidative balance scores correlate with reduced all-cause mortality among hypertensive individuals, indicating better health outcomes.
  • Participants in the highest OBS quartile showed a 28% lower all-cause mortality rate compared to the lowest quartile after considering confounders.
  • This cohort study analyzed NHANES data from 1999-2018, exploring oxidative stress and systemic inflammation's role in mortality rates.
  • Findings highlight the importance of oxidative balance in managing hypertension, suggesting potential avenues for improving patient outcomes.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478d6eehttps://doi.org/10.3389/fcvm.2025.1621911
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of Oxidative Balance Score With All-Cause and Cardiovascular Mortality Among Hypertensive Adults2025
  2. 2The relationship between Oxidation Balance Score and all-cause mortality in patients with hypertension: An observational study2025
  3. 3Association between oxidative balance score with cardiovascular - kidney - metabolic syndrome and all-cause mortality among US population2025 · 1 citations
  4. 4Association between oxidative balance score and mortality: Prospective cohort study in a representative US population2025 · 1 citations
  5. 5The association between oxidative balance score and all-cause and cardiovascular mortality in patients with arthritis: a retrospective cohort study based on the NHANES database (1999–2018)2025