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September 10, 2025World Journal of Traditional Chinese MedicineOpen Access

Synergistic Effects of Betula platyphylla and Dictamnus dasycarpus Formulation on T-Cell Regulation and Atopic Dermatitis Treatment

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Authors

ECEun-Ju ChoiSSS. SungHLHyun‐Su Lee

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Overview

Observational analysis found Betula platyphylla and Dictamnus dasycarpus improved T cell regulation in atopic dermatitis, suggesting a potential herbal treatment.

Key Points

  • BPDD significantly reduced IL-2 and CD69 expression in T cells, indicating its immunomodulatory effects.
  • The formulation inhibited p65 nuclear translocation and activation of MAPK pathways, key in T cell inflammation.
  • In vivo studies showed BPDD alleviated symptoms of atopic dermatitis by reducing skin inflammation and IgE levels.
  • BPDD normalized lymph node size, indicating effective systemic immune regulation in the treatment of atopic dermatitis.

Cite This Study

Choi et al. (2025) studied this question.

synapsesocial.com/papers/68c23f1fb210217d64795779https://doi.org/10.4103/wjtcm.wjtcm_22_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anti-Inflammatory and Barrier-Related Effects of Bidens bipinnata L. Fruit Ethanol Extract in an MC903-Induced AD-like Dermatitis Mouse Model and LPS-Stimulated RAW 264.7 Cells2026
  2. 2Transforming Atopic Dermatitis Management: Probiotics as a Game-Changer in Immune Modulation-A Double-Blind, Placebo-Controlled Clinical Trial.2025
  3. 3BCL-2 Multi-Strain Probiotics for Immunomodulation In Vitro and In Vivo Alleviation of Atopic Dermatitis2025
  4. 4Amygdalin alleviates atopic dermatitis-like skin inflammation via inhibition of Th2 immune responses2025
  5. 5Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions2025 · 22 citations