Molecular Detection of Mycobacterium tuberculosis and Rifampicin Resistance Isolates in Patients Attending Healthcare Facility in Ogoni, Rivers State, Nigeria

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A low prevalence of rifampicin resistance was found at 4.7%, alongside other resistance patterns to anti-TB drugs.
Testing methods revealed 22.7% prevalence using Ziehl Neelsen and 27.3% with GeneXpert, highlighting detection method variability.
The study employed a hospital-based cross-sectional design, utilizing sputum sample analysis and advanced molecular techniques.
Findings emphasize the need for improved anti-tuberculosis strategies to combat the rising trend of multidrug resistance in the region.

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Hospital-based analysis identifies rifampicin-resistant tuberculosis and associated genes in patients, indicating urgent need for drug stewardship.

An et al. (2025) studied this question.

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Hospital-based analysis identifies rifampicin-resistant tuberculosis and associated genes in patients, indicating urgent need for drug stewardship.