September 10, 2025Frontiers in Cellular and Infection MicrobiologyOpen Access

Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure

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Sepsis significantly impairs intestinal barrier function and aggravates inflammatory responses.
Administration of Saccharomyces boulardii led to a notable increase in gut microbiota diversity and abundance.
The treatment reduced the expression of inflammatory markers like IL-6 and TNF-α while enhancing occludin levels.
S. boulardii may play a critical role in maintaining intestinal health during sepsis by favoring beneficial bacteria.

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Implication

Observational analysis shows improved intestinal damage in sepsis with Saccharomyces boulardii, suggesting potential benefits for microbiota diversity.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c23e4fb210217d64791c56 https://doi.org/10.3389/fcimb.2025.1602792

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Implication

Observational analysis shows improved intestinal damage in sepsis with Saccharomyces boulardii, suggesting potential benefits for microbiota diversity.

Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure

Key Points

Discussion

Implication

Cite This Study

Saccharomyces boulardii (CNCM I-745) improves intestinal damage in sepsis by remodeling intestinal flora structure

Key Points

Discussion

Implication

Cite This Study

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