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September 10, 2025Indian Journal of NephrologyOpen Access

The Impact of Epigenomics on Understanding Kidney Diseases

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Authors

SASuraksha Agrawal

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Overview

This review demonstrates how DNA methylation and histone modifications impact kidney diseases, suggesting potential biomarkers for therapy.

Key Points

  • Kidney diseases like AKI and CKD show dysregulation of DNA methylation and histone modifications, impacting function.
  • Investigation of epigenetic mechanisms can identify biomarkers and advance targeted therapies in nephrology.
  • Epigenomic profiling of kidney diseases can lead to improved patient outcomes through precision medicine.
  • Understanding epigenetic changes helps clarify the molecular complexities of kidney disease progression.

Cite This Study

Suraksha Agrawal (2025) studied this question.

synapsesocial.com/papers/68c23e02b210217d64790613https://doi.org/10.25259/ijn_136_2025
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Also Consider

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  1. 1DNA methylation in chronic kidney disease2025 · 8 citations
  2. 2Genome-wide DNA methylation analysis identifies kidney epigenetic dysregulation in a cystinosis mouse model2025
  3. 3Novel approaches and applications in identifying DNA methylation markers of cardio-kidney-metabolic disease.2025
  4. 4The role of N6-methyladenosine (m<sup>6</sup>A) RNA methylation modification in kidney diseases: from mechanism to therapeutic potential2025
  5. 5Advances in the Epigenetic Mechanisms of Diabetic Nephropathy Pathogenesis2025