Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 10, 2025Al-Azhar Assiut Medical JournalOpen Access

The validity of serum autotaxin as a predictor of hepatic fibrosis in patients with nonalcoholic fatty liver disease

View Full Paper
Ask AI
Bookmark
Share

Authors

MAMuhammad Abdel‐GawadHMHala MahfouzMAMona Abdelmeguid

Discussion

Loading...

Member takes

Overview

Cross-sectional analysis evaluates autotaxin for predicting fibrosis in NAFLD patients, suggesting limited validity.

Key Points

  • Autotaxin exhibited poor validity as a fibrosis predictor in nonalcoholic fatty liver disease cases, showing limited diagnostic value.
  • Patients with fibrosis had higher autotaxin levels compared to those without, with a significant difference (P=0.027).
  • This cross-sectional study involved 100 patients assessed for hepatic fibrosis using various scoring systems and bio-markers.
  • Results indicated a gender difference in hypertension prevalence, emphasizing the need for further research on NAFLD's impact.

Cite This Study

Abdel‐Gawad et al. (2023) studied this question.

synapsesocial.com/papers/68c23dc5b210217d6478eb4chttps://doi.org/10.4103/azmj.azmj_10_24
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Correlation of Demography, Liver Function Tests, and Lipid Profile with Fibroscan Results in Patients with Nonalcoholic Fatty Liver Disease Attending a Tertiary Care Hospital in West Bengal2025
  2. 2Association between Nonalcoholic Fatty Liver Disease Severity Assessed by Fibroscan and Atherosclerotic Cardiovascular Disease Risk Score2025 · 1 citations
  3. 3To Determine the Prevalence and Correlation of Atherosclerosis in Patients with Nonalcoholic Fatty Liver Disease2026
  4. 4Evaluation of Platelet Parameters in Relation to Aspartate Aminotransferase to Platelet Ratio Index and Fibrosis-4 Scores among Non-alcoholic Fatty Liver Disease Patients and Healthy Controls: An Exploratory Study2025
  5. 5The Differential Gene Expression Analysis Of Hepatic Inflammatory Genes For Diagnosis Of Early Stages Of Fibrosis In Non Alcoholic Fatty Liver Disease (NAFLD)2024