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September 10, 2025The Journal of Infection in Developing CountriesOpen Access

Assessing the prevalence of antimicrobial resistance among pediatric patients at Kamuzu Central Hospital, Malawi

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Authors

ACAgness C ChitedzeRMRizine MzikamandaTMTarsizio Maida

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Overview

Descriptive study finds high antimicrobial resistance in pediatric patients, indicating urgent guideline revisions.

Key Points

  • High antimicrobial resistance rates were observed, with 47.8% of participants resistant to first-line antibiotics.
  • Among Gram-negative isolates, 32% were Acinetobacter, highlighting significant resistance concerns.
  • The study utilized retrospective analysis of blood culture results over four years to assess resistance patterns.
  • Pediatric care may need revised antibiotic guidelines and enhanced blood culture testing to manage infections better.

Cite This Study

Chitedze et al. (2025) studied this question.

synapsesocial.com/papers/68c23d3ab210217d6478c6a6https://doi.org/10.3855/jidc.20609
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic Underuse and Antimicrobial Resistance Patterns Among Hospitalized Children in a National Referral Hospital in Kenya: A Five-Year Retrospective Study2025
  2. 2Five-year surveillance of antimicrobial resistance patterns among blood culture isolates at the University Teaching Hospital, Kigali, Rwanda2025
  3. 3Bacterial profile and antimicrobial resistance patterns among pediatrics patients with suspected bloodstream infections in Ethiopia: a systematic review and meta-analysis2025
  4. 4A study protocol for the assessment of antibiotic use and bacterial antimicrobial resistance among children under five years of age: implications for a resource-limited setting2025
  5. 5Antimicrobial usage among acutely ill hospitalised children aged 2‒23 months in sub-Saharan Africa and South Asia2025