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August 10, 2025Open Forum Infectious DiseasesOpen Access

Antimicrobial usage among acutely ill hospitalised children aged 2‒23 months in sub-Saharan Africa and South Asia

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Authors

CTCaroline TigoiCBCéline BourdonMNMoses M. Ngari

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Overview

Observational analysis describes antimicrobial prescribing patterns in hospitalized children, indicating potential overuse and need for updated guidelines.

Key Points

  • Antimicrobial use was common, with 91% of children receiving them during their hospital stay, indicating significant use in acute illness.
  • Of 3101 admissions, 1422 (46%) received antimicrobials before hospitalization, and 11% received antimicrobials without indication.
  • The CHAIN cohort study collected daily data on antimicrobial prescribing from nine hospitals over two years, ensuring focused insights.
  • Results highlight overuse and limited adjustment of antimicrobial classes, calling for revised guidelines and clinical trials for better care.

Cite This Study

Tigoi et al. (2025) studied this question.

synapsesocial.com/papers/68af75147567bf4f94fedfa3https://doi.org/10.1093/ofid/ofaf487
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antibiotic Use in Pediatric Care in Ghana: A Call to Action for Stewardship in This Population2025
  2. 2Diagnostic Underuse and Antimicrobial Resistance Patterns Among Hospitalized Children in a National Referral Hospital in Kenya: A Five-Year Retrospective Study2025 · 4 citations
  3. 3A study protocol for the assessment of antibiotic use and bacterial antimicrobial resistance among children under five years of age: implications for a resource-limited setting2025
  4. 4Antimicrobial prescribing patterns among pediatric outpatient encounters in primary healthcare centers in Bujumbura Mairie, Burundi2025
  5. 5Assessing the prevalence of antimicrobial resistance among pediatric patients at Kamuzu Central Hospital, Malawi2025