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September 10, 2025Neurocritical CareOpen Access

Altered Neurocritical Care Management of Patients with Severe Traumatic Brain Injury Following Changed Positions of the Zero-Reference Points for Intracranial and Arterial Pressure Measurement

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Authors

LRLinus RéenHWHenrik WikströmEVEdward Visse

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Overview

Retrospective analysis reveals altered management of intracranial pressure and mean arterial blood pressure in TBI patients, indicating critical implications for care protocols.

Key Points

  • Higher mean intracranial pressure levels were observed after changing the zero-reference point to the external auditory meatus.
  • The use of metoprolol significantly decreased from 50% to 13% after the reference point change, while norepinephrine use increased dramatically from 42% to 98%.
  • The study analyzed over 31,000 measurements from 102 patients with severe traumatic brain injury over two different time periods.
  • These findings highlight the need for careful consideration of zero-reference point placements in traumatic brain injury management protocols.

Cite This Study

Réen et al. (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478bf36https://doi.org/10.1007/s12028-025-02366-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of intracranial pressure monitoring on survival in severe traumatic brain injury: a meta-analysis of randomized trials2025
  2. 2Evaluation of the Prognostic Value and Modifiability of Low-Frequency Pressure Reactivity Index in Patients with Traumatic Brain Injury2025
  3. 3Visualizations of Autoregulatory Insults in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research-Traumatic Brain Injury Cohort Study2025
  4. 4Intracranial Pressure Monitor Insertion in Isolated Traumatic Brain Injury: Does Timing Matter?2025
  5. 5Management and outcome of patients with traumatic brain injury treated in three major Nordic intensive care units: a comparative cohort study2026