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July 14, 2025

Evaluation of the Prognostic Value and Modifiability of Low-Frequency Pressure Reactivity Index in Patients with Traumatic Brain Injury

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Authors

UHUe‐Cheung HoNational Taiwan UniversityNWNathan WeiNational Taiwan UniversityLKLu‐Ting KuoNational Taiwan University Hospital

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Implication

Retrospective analysis evaluates outcomes related to low-frequency pressure reactivity index in TBI patients, suggesting implications for treatment.

Key Points

  • Impaired cerebral autoregulation, represented by elevated LPRx, is linked to poorer outcomes in TBI patients.
  • Higher median LPRx was associated with unfavorable outcomes, indicating its prognostic value for TBI recovery.
  • Methodology included a retrospective analysis of 35 TBI patients monitored for one-minute intervals in ICU settings.
  • Despite potential as a continuous measure, the clinical utility of LPRx and CPPopt remains uncertain due to inconsistent responses to therapies.

Cite This Study

Ho et al. (2025) studied this question.

synapsesocial.com/papers/689a02b6e6551bb0af8cc29chttps://doi.org/10.21203/rs.3.rs-7029976/v1
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