Endoscopic Program With a Scoring System for Surveillance of Metachronous Esophageal Cell Carcinoma for Older Patients Considering Risk Factors

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Discussion

Observational analysis shows risk factors for metachronous esophageal carcinoma in older patients, indicating the need for improved surveillance.

Body mass index lower than 18.5 and Charlson comorbidity index of 2 or higher significantly affect overall survival.
Cox regression analysis identified non-older age, Lugol-voiding lesions, and head and neck cancer as key risk factors for metachronous ESCC.
A significant drop in overall survival rates was noted in high-score groups for metachronous ESCC after endoscopic resection.
An endoscopic surveillance scoring system was developed to better monitor metachronous ESCC in older adults.

Naito et al. (2025) studied this question.

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Observational analysis shows risk factors for metachronous esophageal carcinoma in older patients, indicating the need for improved surveillance.