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September 10, 2025Diabetes/Metabolism Research and ReviewsOpen Access

Endothelial Dysfunction and Therapeutic Advances in Chronic Kidney Disease

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Authors

LFLiang FengLGLi GuiKCKehong Chen

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Overview

This review highlights novel interventions for endothelial dysfunction in chronic kidney disease, suggesting improved patient outcomes.

Key Points

  • Endothelial dysfunction is a key mechanism in chronic kidney disease that contributes to cardiovascular risk.
  • Recent treatment strategies, including dual endothelin-angiotensin receptor antagonists, have shown protective effects on endothelial cells.
  • Research is expanding into anti-ageing therapies, indicating new directions for improving endothelial function in CKD.
  • Combining lifestyle changes with pharmacological therapies may enhance protection against endothelial dysfunction and improve health.

Cite This Study

Feng et al. (2025) studied this question.

synapsesocial.com/papers/68c23cf6b210217d6478b3a1https://doi.org/10.1002/dmrr.70086
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Also Consider

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  1. 1Therapeutic approaches in the management of chronic kidney disease: the past, the present, and the future2025
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  4. 4Advancements in Pharmacotherapy for Diabetic Kidney Disease: A Systematic Review2025 · 7 citations
  5. 5Contemporary and Emerging Therapeutics in Cardiovascular-Kidney-Metabolic (CKM) Syndrome: In Memory of Professor Akira Endo2025 · 1 citations