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September 10, 2025Onderstepoort Journal of Veterinary Research

Comparing the toxicity of selected plant extract anthelmintics to levamisole hydrochloride and piperazine citrate in chickens

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Authors

JKJohn KatereggaANAgnes Sarah NalulePVPatrick Vudriko

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Overview

Controlled experiment examines toxicity of plant anthelmintics relative to levamisole and piperazine in chickens, highlighting potential risks.

Key Points

  • CPLe significantly raised albumin compared to CAFe, suggesting different levels of liver impact.
  • Levamisole increased AST levels more than CAFe, indicating hepatic strain from synthetic treatment.
  • All extracts and drugs elevated eosinophil counts, reflecting an increased inflammatory response in the chickens.
  • CPLa, CAFe, CAFa, and levamisole were toxic to kidneys, emphasizing that plant extracts are not always safer.

Cite This Study

Kateregga et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d6478aaaehttps://doi.org/10.4102/ojvr.v92i1.2212
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1In Vitro Anthelmintic Effect of <em>Piper auritum</em> Kunth and <em>Capsicum annuum </em>L. on Goat Intestinal Nematodes2025
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  3. 3Comparative Evaluation of Hematological and Biochemical Safety Profiles of Chitosan Nano-encapsulated Bromelain Formulations with Levamisole in Goats Under Tropical Smallholder Systems2025
  4. 4In vivo anthelmintic effects of polyphenol-rich extracts from the salt-tolerant species Cladium mariscus (L.) Pohl, 1809 and Limoniastrum monopetalum (L.) Boiss., 1848 against gastrointestinal parasitic nematodes in lambs2025
  5. 5Effectiveness of Calotropis procera Leaf Extract in Treating Eimeriosis- Induced Inflammation Alteration of the Jejunum in Mice2025