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September 10, 2025Frontiers in MedicineOpen Access

Global and Chinese trends in acute myeloid leukemia burden (1990–2021): a comprehensive analysis based on the GBD study

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Authors

XLXiaojing LuXPXin PengYZYunxiang Zhang

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Overview

Analysis demonstrates a 73.8% increase in global AML deaths, while China's rates decline, highlighting health disparities.

Key Points

  • Globally, AML deaths increased by 73.8%, indicating rising health concerns.
  • China experienced a 14.76% reduction in age-standardized mortality rates, suggesting improved healthcare.
  • Analysis of GBD data utilized Joinpoint regression to assess mortality trends and risk factors.
  • Smoking continues to be the leading risk factor for AML, highlighting the need for targeted interventions.

Cite This Study

Lu et al. (2025) studied this question.

synapsesocial.com/papers/68c23caeb210217d64789c29https://doi.org/10.3389/fmed.2025.1629111
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  5. 5Geographic, demographic, and risk factor profiles of acute myeloid and acute lymphoblastic leukemia in the United States: Insights from the global burden of disease study 20212025