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September 10, 2025Frontiers in Bioengineering and BiotechnologyOpen Access

3D-printed artificial bone scaffolds: the design of materials, the incorporation of bioactive substances, and the integration of vascularized tissue flaps

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Authors

QDQida DuanHSHongda ShaoNLNing Luo

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Overview

This review highlights the role of bioactive factors and vascularization in scaffolds, suggesting new strategies for tissue engineering.

Key Points

  • 3D-printed bone scaffolds significantly improve regeneration efficiency and promote vascularization.
  • Integration of osteogenic and angiogenic mechanisms through vascularized scaffolds may overcome traditional graft limitations.
  • The study presents strategies for incorporating bioactive factors to enhance bone healing and development.
  • This review emphasizes a shift towards scaffolds that support biological functions rather than just structural support.

Cite This Study

Duan et al. (2025) studied this question.

synapsesocial.com/papers/68c23c20b210217d647876b8https://doi.org/10.3389/fbioe.2025.1614727
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