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December 4, 2025APL MaterialsOpen Access

3D-printed oxygen-releasing scaffolds promote bone repair via angiogenesis and osteogenesis

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Authors

PLPengyuan LengCSChuchu Sun

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Overview

This analysis demonstrates improved bone regeneration in models with 3D-printed scaffolds, suggesting novel approaches for tissue regeneration.

Key Points

  • Bone regeneration was significantly enhanced using 3D-printed scaffolds in a rat model, achieving effective vascular network formation.
  • The scaffolds, made of polycaprolactone and hydroxyapatite, showed superior mechanical properties and supported sustained oxygen release.
  • Using fused deposition modeling, the scaffolds exhibited excellent
  • promoting both osteogenesis and angiogenesis, with hypoxia as a significant factor influencing outcomes.

Cite This Study

Leng et al. (2025) studied this question.

synapsesocial.com/papers/6930dc9eea1aef094cca2e17https://doi.org/10.1063/5.0305073
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