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September 10, 2025

Relationship Between Total 25-Hydroxyvitamin D and Parathyroid Hormone Concentrations During Early Gestation in Indian Women.

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Authors

NCN. N. ChopraFAFathima AyoobCRC Roopashree

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Overview

Assessment shows lower vitamin D diagnostic threshold in early pregnancy, indicating need for re-evaluation.

Key Points

  • A new diagnostic threshold for vitamin D deficiency was found at 15.76 ng/mL, suggesting significant implications for pregnancy care.
  • Using this lower cutoff, 66.1% of pregnant women were identified as vitamin D deficient, compared to 82.0% at the standard threshold.
  • Segmented regression analysis demonstrated the inverse relationship between parathyroid hormone and vitamin D levels in early pregnancy.
  • Factors like parity, season, anemia status, and physical activity were significantly associated with vitamin D deficiency in this population.

Cite This Study

Chopra et al. (2025) studied this question.

synapsesocial.com/papers/68c23b8fb210217d64785433https://doi.org/10.3390/nu17162626
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Correlation Between Plasma Vitamin D and Blood Parameters in Prenatal Women2025
  2. 2Prevalence of Vitamin D Deficiency in Pregnant Women: Systematic Review and Meta-analysis2025 · 5 citations
  3. 3Vitamin D deficiency and preterm birth: results of a clinical study2025
  4. 4Can vitamin D supplementation be dangerous? 25-Hydroxyvitamin D and 1,25-hydroxyvitamin D concentration in healthy population and primary hyperparathyroidism: a single-center experience and literature review2025
  5. 5Relationship of Maternal 25-Hydroxyvitamin D₃ Deficiency With the Occurrence of Preterm Labor2026