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September 10, 2025Pediatric CardiologyOpen Access

Application of the New 2023 World Heart Federation Criteria to Rheumatic Heart Disease in the Setting of First Episode of Acute Rheumatic Fever: Predictors for Resolution

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Authors

JWJacqueline WilliamsonGWGillian WhalleyJMJames Marangou

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Overview

Cohort study identifies echocardiographic markers predicting rheumatic heart disease resolution in children, implying importance of early diagnosis.

Key Points

  • Resolution of rheumatic heart disease occurred in 19% of patients, with early RHD at diagnosis being a strong predictor.
  • Baseline absence of mitral valve thickening was associated with resolution, highlighting its diagnostic importance.
  • This retrospective cohort study included 165 children diagnosed with both acute rheumatic fever and rheumatic heart disease.
  • Multivariate analysis confirmed that early RHD significantly predicts the likelihood of resolution of valvular disease.

Cite This Study

Williamson et al. (2025) studied this question.

synapsesocial.com/papers/68c23b4ab210217d64783d9fhttps://doi.org/10.1007/s00246-025-03966-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Impact of Acute Rheumatic Fever Diagnosis on Rheumatic Heart Disease Severity2025
  2. 2Acute Rheumatic Fever and Rheumatic Heart Disease in Children Aged Less Than 5 Years in the Northern Territory Between 2010 and 20202025
  3. 3Clinical Characteristics, Echocardiographic Features And Short-Term Outcomes of Children with Rheumatic Heart Diseas2025
  4. 4The epidemiology of acute rheumatic fever and rheumatic heart disease in Queensland, 2017–2021: a population‐level cohort study using linked administrative data2025
  5. 5Progressive deterioration in clinical outcome in RHD: influence of therapeutic interventions2025