Hypervirulent Carbapenem-resistant Klebsiella pneumoniae Infection: Epidemiology, Virulence, Resistance, and Treatment

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Review summarizes virulence and resistance characteristics of hypervirulent Klebsiella pneumoniae, highlighting treatment challenges.

Hypervirulent carbapenem-resistant Klebsiella pneumoniae shows significant virulence and resistance traits, creating treatment challenges.
Increased strains of hypervirulent Klebsiella pneumoniae may resist colistin and tigecycline, complicating management efforts.
Analysis covers epidemiology, resistance genes, and potential treatment modalities for hypervirulent Klebsiella pneumoniae.
Understanding the interaction between virulence and resistance may aid in developing effective treatment strategies.

Yu et al. (2025) studied this question.

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