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September 10, 2025Saudi Journal of MedicineOpen Access

Cancer Cachexia: A Meta-Analysis of Prevalence, Outcomes, and Interventions

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Authors

DADr Sharique AhmadDWDaanyaal Wasim

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Overview

Meta-analysis shows cancer cachexia affects 49.2% of patients, highlighting the need for improved interventions.

Key Points

  • Cachexia prevalence in advanced cancer patients is significantly high at 49.2%, with lung and pancreatic cancers most affected.
  • The risk of mortality in cachexia patients increases by 41%, demonstrating its critical clinical implications.
  • Nutritional interventions alone lack effectiveness, while multimodal approaches enhance weight stabilization and quality of life.
  • Anamorelin shows moderate effectiveness in increasing lean body mass, but its impact on survival remains unclear.

Cite This Study

Ahmad et al. (2025) studied this question.

synapsesocial.com/papers/68c23b08b210217d64782709https://doi.org/10.36348/sjm.2025.v10i08.009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cancer Cachexia in Clinical Practice: A Review of Treatment Barriers Among Cancer Patients2025 · 1 citations
  2. 2Understanding Immunomodulation and Managing Cancer Cachexia: A Narrative Review2025
  3. 3Cancer therapy and cachexia2025
  4. 4A health-system-scale, episode-resolved multimodal atlas of cancer cachexia2025
  5. 5The cachexia hematologic severity score (CHeSS): Use of a laboratory-based tool to predict survival and mutation-associated wasting in Acute Myeloid Leukemia and myelodysplastic syndrome2025