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July 15, 2025Clinical Cancer Drugs

Understanding Immunomodulation and Managing Cancer Cachexia: A Narrative Review

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Authors

LZLingbing ZhangXZXun Zhu

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Overview

This narrative review highlights systemic inflammation and therapy options for managing cancer cachexia in patients.

Key Points

  • Cancer cachexia significantly reduces quality of life and survival in advanced cancer patients.
  • The review discusses the dysregulated host-tumor interaction contributing to altered metabolism and immune homeostasis.
  • Current treatments include exercise, nutritional support, and immunomodulatory strategies with various effectiveness.
  • A multimodal approach integrating physical activity, nutritional support, and pharmacological interventions is essential for management.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc801https://doi.org/10.2174/012212697x400236250630115449
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