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September 5, 2025Biodiversitas Journal of Biological DiversityOpen Access

Quantification of 1-deoxynojirimycin content, ?-amylase inhibition activity, and secondary metabolites in four different mulberry accession leaves from Indonesia

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Authors

YWYasinta Ratna Esti WulandariWFWilliam FransYYYanti Yanti

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Overview

Analysis reveals higher 1-deoxynojirimycin and a-amylase inhibition in mulberry from Bogor, suggesting potential health benefits.

Key Points

  • Accession 3 from Bogor showed the highest 1-deoxynojirimycin content at 0.357 mg 1-DNJ/g leaves.
  • This accession also demonstrated the best a-amylase inhibition with an IC50 value of 5.1075 mg/mL.
  • Samples were analyzed for content using HPLC and tested for enzyme activity through in-vitro methods.
  • Findings highlight the potential of mulberry as an antidiabetic, with a need for future in-vivo studies.

Cite This Study

Wulandari et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477ee46https://doi.org/10.13057/biodiv/d260647
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Critical Review of 1-Deoxynojirimycin (DNJ) 
in Mulberry in Curing Diabetes Mellitus2025
  2. 2Therapeutic Prospects of Mulberry-Derived DNJ: A Review2025
  3. 3Virtual screening of metabolites from mulberry (Morus alba L.) leaves as anti-hyperglycemic agents through molecular docking against multiple targets2025
  4. 4Insights into the Activities and Usefulness of Deoxynojirimycin and Morus alba: A Comprehensive Review2025
  5. 5Phytochemical Composition and Health Benefits of Mulberry Plant Parts: A Review2025