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September 5, 2025Bulletin of the National Research Centre/Bulletin of the National Research CenterOpen Access

The efficacy of ‘ready-to-use therapeutic food - RUTF’ without milk to modulate severe acute malnutrition (SAM) in low- and middle-income countries (LMICs): a scoping review

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Authors

FDFrancis DansoITIhab Tewfik

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Overview

Scoping review shows non-milk RUTF achieves comparable outcomes in SAM cases across LMICs, indicating its potential as a cost-effective alternative.

Key Points

  • Non-milk RUTF produced comparable weight gain to standard RUTF, showing promise for SAM treatment.
  • Recovery rates for non-milk RUTF ranged from 54 to 90%, suggesting its effectiveness in children with SAM.
  • Haemoglobin levels improved significantly in anaemic children treated with non-milk RUTF, enhancing iron status.
  • Mortality and morbidity rates were similar between non-milk RUTF and standard RUTF, supporting its viability.

Cite This Study

Danso et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477ea22https://doi.org/10.1186/s42269-025-01355-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors Influencing Recovery and Mortality in Children with Severe Acute Malnutrition (SAM): Insights from a Therapeutic Feeding Program2025
  2. 2Insect and Pulse-Based Ready-to-Use Therapeutic Food as an Alternative to Standard Milk-and Peanut Paste-Based Formulation for Treating Childhood Malnutrition2025
  3. 3Adherence to ready-to-use therapeutic food in older children with sickle cell anaemia and severe acute malnutrition: a mixed-methods study in a low-income setting.2025
  4. 4Early weight gain predicts nutritional recovery in children with sickle cell anemia and severe acute malnutrition in Nigeria2025
  5. 5Moringa Bean Cake as A Ready to Use Therapeutic (RUTF) Ingridient in Malnourished Children Aged 12-59 Months in Maluku Province: A Multicenter Project2025