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December 8, 2025BloodOpen Access

Early weight gain predicts nutritional recovery in children with sickle cell anemia and severe acute malnutrition in Nigeria

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Authors

SAShehu U. AbdullahiHKHalima KabirKSKhadija A. Shamsu

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Overview

Feasibility trial shows early weight gain predicts improved recovery in malnourished children with sickle cell anemia, suggesting tailored interventions are needed.

Key Points

  • Nutritional recovery improved with early weight gain in children with sickle cell anemia and severe malnutrition, highlighting intervention importance.
  • Of 66 children evaluated after 12 weeks, only 11 achieved recovery, emphasizing the necessity for early intervention measures.
  • Assessment during a multicenter randomized controlled trial showed that logistic regression can identify predictors of recovery.
  • Outcomes may be optimized by integrating nutrition education and vocational training to tackle socioeconomic barriers to treatment success.

Cite This Study

Abdullahi et al. (2025) studied this question.

synapsesocial.com/papers/69362f5a4fa91c937236db0dhttps://doi.org/10.1182/blood-2025-4717
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Adherence to ready-to-use therapeutic food in older children with sickle cell anaemia and severe acute malnutrition: a mixed-methods study in a low-income setting.2025
  2. 2Rate and time of recovery and its predictors among children aged 6–59 months admitted to inpatient therapeutic feeding centers for the treatment of severe acute malnutrition in Sana’a, Yemen: a prospective cohort study2025
  3. 3Combined nutrition education and vocational training for caregivers of children with sickle cell anemia and severe malnutrition: A feasibility study2025
  4. 4Factors Influencing Recovery and Mortality in Children with Severe Acute Malnutrition (SAM): Insights from a Therapeutic Feeding Program2025
  5. 5Malnutrition and associated factors in school-age children with sickle cell anemia2025