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September 5, 2025Journal of Neonatal-Perinatal Medicine

Antibiotic prophylaxis for neonatal surgery: Evaluation of the implementation of a new protocol based on “less could be better”

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Authors

MTM. ToroMMMarga Martı́nCPCelia Permuy

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Overview

A case-control study assesses the impact of a new surgical protocol on infection complications and antibiotic duration.

Key Points

  • The protocol change led to a significant reduction in antibiotic duration to 48 hours, enhancing patient outcomes.
  • Surgical site infections occurred at comparable rates, with 6.4% in the intervention group and 10.1% in the control group, indicating safety.
  • This case-control study analyzed 90 neonatal procedures versus 116 historical controls to assess play of protocol adherence.
  • Implementing a narrower antibiotic spectrum in postoperative care shows feasibility in neonatal surgical settings.

Cite This Study

Toro et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477bbeahttps://doi.org/10.1177/19345798251374926
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of prophylactic antibiotic duration on surgical site infection rate in neonatal surgery: a multicenter retrospective observational study2025
  2. 2Perioperative antibiotic prophylaxis in pediatric vertebrology: short or long course?2025
  3. 3Optimizing Surgical Prophylaxis: An Audit of Antibiotic Use and Guideline Adherence in a Tertiary Care Hospital with Focus on Antimicrobial Stewardship2025
  4. 4Association between Timing of Prophylactic Antibiotic in Cesarean Section and Risk of Postpartum and Neonatal Infections2025
  5. 5The Six S’s of Surgical Antibiotic Prophylaxis in Pediatrics: A Pragmatic Approach2025