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September 5, 2025International Journal of Community Medicine and Public HealthOpen Access

Comparative efficacy of carbetocin versus oxytocin in preventing postpartum hemorrhage during lower segment cesarean section: a prospective randomized controlled trial

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Authors

ASArti G. SuryawanshiSKSanjay K. KachhaveSDSatishkumar Dhage

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Overview

This randomized controlled trial compares carbetocin and oxytocin, revealing carbetocin's lower PPH incidence in patients.

Key Points

  • Carbetocin significantly reduced postpartum hemorrhage rates at 3.3%, compared to 15.0% with oxytocin.
  • The carbetocin group experienced a mean blood loss of 435.2 ml, significantly lower than 624.7 ml in the oxytocin group.
  • Only 5% of carbetocin patients needed additional uterotonics, while 18.3% in the oxytocin group did.
  • Blood transfusion requirements were lower in the carbetocin group at 1.7% versus 8.3% in the oxytocin group.

Cite This Study

Suryawanshi et al. (2025) studied this question.

synapsesocial.com/papers/68c23965b210217d6477b31ahttps://doi.org/10.18203/2394-6040.ijcmph20252839
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A comparative study on the efficacy of intravenous oxytocin and carbetocin in the prevention and management of postpartum hemorrhage in tertiary care hospital in Uttar Pradesh, India2025
  2. 2Comparative Side Effects of Carbetocin vs Oxytocin in Prevention of Postpartum Bleeding Following Cesarean Sections2025
  3. 3Intramyometrial and Intravenous Oxytocin Compared With Intravenous Carbetocin for Prevention of Postpartum Hemorrhage in Elective Cesarean Section: A Quasirandomized Controlled Phase IV Noninferiority Interventional Trial2025 · 1 citations
  4. 4Carbetocin vs Oxytocin for Prevention of Postpartum Hemorrhage in Cesarean Delivery: A Systematic Review and Meta-Analysis2025
  5. 5Carbetocin in the prevention of postpartum hemorrhage2025