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September 10, 2025Journal of Obstetrics Gynecology and Cancer ResearchOpen Access

Carbetocin vs Oxytocin for Prevention of Postpartum Hemorrhage in Cesarean Delivery: A Systematic Review and Meta-Analysis

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Authors

JJJohnny JohnnyJNJessica NathaliaCCCasey Christiany

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Overview

Systematic review and meta-analysis assess the impact on postpartum blood loss and hemoglobin levels.

Key Points

  • Carbetocin significantly reduces postpartum blood loss compared to oxytocin, improving maternal outcomes.
  • In a meta-analysis of six randomized controlled trials, carbetocin showed a risk ratio of -47.71 for blood loss volume.
  • Despite benefits in blood loss, postpartum hemoglobin levels did not differ significantly between carbetocin and oxytocin.
  • Further clinical trials are needed to fully validate carbetocin's effectiveness in preventing postpartum hemorrhage.

Cite This Study

Johnny et al. (2025) studied this question.

synapsesocial.com/papers/68c23d81b210217d6478de82https://doi.org/10.24200/jogcr.10.10.789
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