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September 5, 2025Oncology ReviewsOpen Access

Non-coding RNAs as novel biomarkers and therapeutic targets in breast cancer

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Authors

VBVeronica BarbiSMSara De MartinoAAAurora Aiello

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Overview

This review highlights the role of non-coding RNAs in breast cancer heterogeneity and their potential as biomarkers and therapeutic targets.

Key Points

  • Non-coding RNAs play a critical role in breast cancer biology, influencing tumor initiation, progression, and treatment resistance.
  • Distinct expression profiles of non-coding RNAs across breast cancer subtypes underscore their potential as effective biomarkers and therapeutic targets.
  • This review explores the multifaceted functional roles of non-coding RNAs in breast cancer and their implications for personalized medicine.
  • Understanding the complex mechanisms behind non-coding RNAs can lead to innovative strategies for better managing breast cancer patients.

Cite This Study

Barbi et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477ac0dhttps://doi.org/10.3389/or.2025.1621144
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Functional Heterogeneity and Context-Dependent Roles of LncRNAs in Breast Cancer2025
  2. 2Non‐Coding <scp>RNAs</scp> in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials2025
  3. 3Regulatory mechanisms and emerging diagnostic and therapeutic opportunities of non-coding RNAs in tumorigenesis: a pan-cancer perspective2025
  4. 4The Role of Non-Coding Regions in Breast Cancer: From Gene Regulation to Therapeutic Implications2025
  5. 5The Role of Non-Coding RNAs in the Regulation of Oncogenic Pathways in Breast and Gynaecological Cancers2025