September 5, 2025Clinical Pediatrics

Perinatal Factors Associated With Congenital Hypothyroidism in Very Low Birth Weight Infants: A Retrospective Cohort Study

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Authors

YJYufeng JinSun Yat-sen University QZQ F Zhang YBYingying BaoWomen's Hospital, School of Medicine, Zhejiang University

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Implication

Retrospective cohort study identifies maternal thyroid disease and patent ductus arteriosus as risk factors for congenital hypothyroidism in very low birth weight infants.

Key Points

Congenital hypothyroidism (CH) incidence is higher in severely low birth weight infants, reaching 11.1% in extremely low birth weight infants.
Maternal thyroid disease and patent ductus arteriosus independently increase the risk of congenital hypothyroidism, with odds ratios of 2.12 and 2.25 respectively.
Higher birth weight shows a marginally protective effect against congenital hypothyroidism, suggesting weight monitoring is important.
Dynamic thyroid monitoring in very low birth weight populations is essential, particularly for those with maternal thyroid disease.

Cite This Study

Jin et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a795 https://doi.org/10.1177/00099228251370565

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Implication

Retrospective cohort study identifies maternal thyroid disease and patent ductus arteriosus as risk factors for congenital hypothyroidism in very low birth weight infants.

Perinatal Factors Associated With Congenital Hypothyroidism in Very Low Birth Weight Infants: A Retrospective Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Perinatal Factors Associated With Congenital Hypothyroidism in Very Low Birth Weight Infants: A Retrospective Cohort Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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