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September 5, 2025In VivoOpen Access

Association Between Frailty and Use of Potentially Inappropriate Medications in Elderly Hospitalized Patients: A Cross-Sectional Study

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Authors

YMYasuhiro MorisakiAMAyako Maeda‐MinamiMSMasaki Sato

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Overview

Cross-sectional analysis reveals no significant difference in PIM use between frail and non-frail patients, highlighting critical prescribing considerations.

Key Points

  • The study found no significant difference in PIM use between frail and non-frail elderly patients.
  • Adjusted odds ratio for PIM use was 1.29, indicating similar use rates for frailty status.
  • Sensitivity analysis showed that PIM use was significantly higher in patients with severe frailty (odds ratio 12.0).
  • This underscores the need for careful medication management in elderly patients, especially those with severe frailty.

Cite This Study

Morisaki et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64779185https://doi.org/10.21873/invivo.14099
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pre-admission Administration of Inappropriate Medications in Geriatric Patients Admitted to a Tertiary Care Teaching Hospital2025
  2. 2Associations of potentially inappropriate medications in older adults with mortality and hospitalizations: methodological challenges in pharmacoepidemiology2025 · 3 citations
  3. 3Polypharmacy and the Use of Potentially Inappropriate Medications in Elderly People in Nursing Homes: A Cross-Sectional Study2025 · 1 citations
  4. 4Potentially inappropriate medication in homebound older adults receiving home medical care2025
  5. 5Potentially Inappropriate Medication and Associated Factors Among Older Patients with HIV/AIDS: A Multicenter Cross-Sectional Study2025 · 3 citations