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December 8, 2025Journal of Ageing and LongevityOpen Access

Polypharmacy and the Use of Potentially Inappropriate Medications in Elderly People in Nursing Homes: A Cross-Sectional Study

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Authors

EPEzequiel PintoAlgarve Biomedical CenterHLHelena S. LeitãoUniversity of Algarve

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Overview

Cross-sectional study highlights polypharmacy and adverse drug events in elderly people, suggesting review needs in nursing homes.

Key Points

  • This research aims to describe the prevalence and predictors of polypharmacy and potentially inappropriate medications in nursing home residents.
  • Conducted a cross-sectional study among 151 nursing home residents aged ≥ 65 years.
  • Extracted data from institutional records regarding medication use.
  • Analyzed sociodemographic and clinical characteristics associated with medication use.
  • 49.7% of residents experienced excessive polypharmacy.
  • 94% of the sample had potential drug-drug interactions (PDDIs).
  • 82.8% of residents used potentially inappropriate medications (PIMs).
  • Proton pump inhibitors and anxiolytics were the most common PIMs.

Cite This Study

Pinto et al. (2025) studied this question.

synapsesocial.com/papers/693624ce4fa91c937236cd98https://doi.org/10.3390/jal5040054
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pre-admission Administration of Inappropriate Medications in Geriatric Patients Admitted to a Tertiary Care Teaching Hospital2025
  2. 2Potentially inappropriate medication in homebound older adults receiving home medical care2025
  3. 3The Prevalence and Impact of Polypharmacy and Potentially Inappropriate Medications in Australian Residential Aged Care Facilities: A Narrative Review2024
  4. 4Drug-Related Problems in Institutionalized Older Adults: A Cross-Sectional Study of Prevalence and Risk Factors2025
  5. 5Potentially Inappropriate Medication and Associated Factors Among Older Patients with HIV/AIDS: A Multicenter Cross-Sectional Study2025 · 3 citations