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September 5, 2025International journal of clinical metabolism and diabetes.

Insulin Resistance in Type 2 Diabetes with Periodontal Disease and Comparison of Various Surrogate Markers: HOMA IR, HOMA IR Using C peptide, and Triglyceride Glucose Index

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Authors

RPRajadurai Arul PrakashPAPoongothai ArulprakashNTNirmal Tony

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Overview

Cross-sectional study finds increased insulin resistance in Type 2 diabetes patients with periodontal disease, indicating significant correlations with surrogate markers.

Key Points

  • Insulin resistance was significantly higher in type 2 diabetes patients with periodontal disease compared to controls.
  • HOMA IR using C-peptide and triglyceride glucose index showed a strong positive correlation with the insulin-based HOMA IR method.
  • No significant differences in insulin resistance were observed across genders or various stages of periodontal disease.
  • The triglyceride glucose index is cost-effective and simple to calculate, supporting its use for insulin resistance identification.

Cite This Study

Prakash et al. (2025) studied this question.

synapsesocial.com/papers/68c23887b210217d6477860ehttps://doi.org/10.1177/30502071251360486
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beyond HOMA-IR: Comparative Evaluation of Insulin Resistance and Anthropometric Indices Across Prediabetes and Type 2 Diabetes Mellitus in Metabolic Syndrome Patients2025 · 2 citations
  2. 2A-038 Correlation of the insulin resistance index (HOMA IR) with oral glucose tolerance test (OGTT) and glycated hemoglobin (A1c) in subjects without diagnosed diabetes mellitus2025
  3. 3TRIGLYCERIDE–GLUCOSE INDEX REVEALS HIGH INSULIN-RESISTANCE BURDEN IN INDIAN RHEUMATOID-ARTHRITIS PATIENTS2025
  4. 4The relationship between novel inflammatory markers SII, SIRI, MHR, UHR and insulin resistance in patients with type 2 diabetes: based on a retrospective analysis2025
  5. 5Lipid accumulation product index and TG/HDL-C as a predictor for insulin resistance in diabetes mellitus - A cross-sectional pilot study2025