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September 5, 2025World Journal of Clinical Cases

Mini-review on insulin resistance assessment: Advances in surrogate indices and clinical applications

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Authors

KMKengo Moriyama

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Overview

This mini-review discusses surrogate indices for insulin resistance in metabolic disorders, emphasizing their strengths and limitations.

Key Points

  • Surrogate indices for insulin resistance can enhance early detection of metabolic disorders, guiding interventions.
  • The homeostasis model assessment and Matsuda index are critical tools highlighted for their clinical utility in assessing insulin resistance.
  • The hyperinsulinemic-euglycemic clamp is a gold standard but not widely applicable due to its complexity.
  • Ethnic background and disease status can affect the applicability of insulin resistance indices in diverse populations.

Cite This Study

Kengo Moriyama (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d647774e9https://doi.org/10.12998/wjcc.v13.i29.108380
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Also Consider

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  1. 1Beyond HOMA-IR: Comparative Evaluation of Insulin Resistance and Anthropometric Indices Across Prediabetes and Type 2 Diabetes Mellitus in Metabolic Syndrome Patients2025 · 2 citations
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  3. 3Comparison of nine insulin resistance surrogates for predicting cardiovascular disease: a cohort study2025 · 10 citations
  4. 4Diagnostic accuracy of various anthropometric indexes for assessing insulin resistance in the Peruvian population: An analytical cross-sectional study2025
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