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September 5, 2025JACC Case ReportsOpen Access

Imagenomics and Ventricular Arrhythmia

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Authors

CMChiara MartiniDSDavide Maria ScordoABAlessio Borrelli

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Overview

Observational analysis found complex arrhythmogenic mechanisms in a patient with ventricular arrhythmias, suggesting implications for precision medicine.

Key Points

  • Ventricular tachycardia was induced in a patient, leading to an implantable cardioverter-defibrillator placement.
  • Cardiac imaging revealed a nonischemic scar in the left ventricle, indicating a risk factor for arrhythmias.
  • Genetic testing identified a TECRL variant associated with a hereditary arrhythmia disorder, informing treatment strategies.
  • The study emphasizes the importance of combining cardiac imaging and genetics for better patient management.

Cite This Study

Martini et al. (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d64776bc8https://doi.org/10.1016/j.jaccas.2025.104938
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mapping and Ablation of Ventricular Tachycardia in Nonischemic Left Ventricular Cardiomyopathy2026
  2. 2Case Report: From multimodality imaging to catheter ablation of ventricular arrhythmias in arrhythmogenic mitral valve prolapse2025
  3. 3Beyond Tachycardia-Induced Cardiomyopathy2025
  4. 4Occult Idiopathic Ventricular Fibrillation After Preoperative Cardiovascular Evaluation2026
  5. 5Syncope and Scar in a Former Elite Basketball Player2026