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September 10, 2025JACC Case ReportsOpen Access

Beyond Tachycardia-Induced Cardiomyopathy

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Authors

AKAlexander KongTBTeresa BernardesERElona Rrapo-Kaso

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Overview

Case report highlights genetic link to arrhythmia-induced cardiomyopathy, suggesting ABCC9's role in heart failure.

Key Points

  • The identified ABCC9 gene variant suggests a genetic component to arrhythmia-induced cardiomyopathy.
  • Improved ventricular function followed rhythm control in a patient with tachycardia-induced cardiomyopathy.
  • Genetic testing revealed a likely pathogenic variant in a patient with atrial fibrillation and heart failure.
  • This case emphasizes the importance of genetic testing in diagnosing atypical cardiomyopathies.

Cite This Study

Kong et al. (2025) studied this question.

synapsesocial.com/papers/68d413ee713b0b5dfea61887https://doi.org/10.1016/j.jaccas.2025.105302
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tachycardia-induced cardiomyopathy: evolution of the concept and contemporary insights2026
  2. 2A Review of Cardiomyopathy Gene Variants as Drivers of Early-Onset Atrial Fibrillation: Linking Genotype to Phenotype in Precision Medicine2026
  3. 3A Review of Cardiomyopathy Gene Variants as Drivers of Early-Onset Atrial Fibrillation: Linking Genotype to Phenotype in Precision Medicine2026
  4. 4Early onset atrial fibrillation as a marker of inherited cardiomyopathy: lessons from combined imaging and genetic assessment2026
  5. 5Tachycardia induced cardiomyopathy as a hidden cause of Heart failure in Pediatrics; A retrospective single-centre study2024