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August 17, 2025Indus journal of bioscience research.Open Access

The Association of Anti-Cyclic Citrullinated Peptide Positivity with Extra-Articular Manifestations in Patients with Rheumatoid Arthritis

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Authors

MSMuhammad SohailAKAtta Muhammad KhanRAR Amin

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Overview

Cross-sectional study shows anti-CCP positivity relates to disease activity in RA patients, suggesting monitoring may be critical.

Key Points

  • ExRA was found in 9.9% of patients, with rheumatoid nodules being the most common manifestation.
  • High DAS-28 scores (>5.1) were significantly associated with the presence of ExRA (p = 0.032).
  • Observational study recruited 91 patients with RA, gathering demographic, clinical, and serological data.
  • While ExRA commonly occurred with anti-CCP positivity, the relationship was not statistically significant (p = 0.391).

Cite This Study

Sohail et al. (2025) studied this question.

synapsesocial.com/papers/68c2368eb210217d64774bdahttps://doi.org/10.70749/ijbr.v3i7.2015
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Diagnostic Efficacy of Anticyclic Citrullinated Peptide Antibody in Diagnosis of Rheumatoid Arthritis2025
  2. 2The Value of Rheumatoid Arthritis Citrullinated Peptides (<scp>RACP</scp>) System in the Diagnosis of Rheumatoid Arthritis: A Retrospective Analysis of 2632 Patients2025
  3. 3Factors related to seroconversion of anti-cyclic citrullinated peptide antibody after the onset of rheumatoid arthritis: a case-control study and systematic review2025 · 1 citations
  4. 4Comparison of Anti-cyclic citrullinated peptide antiboby and Rheumatoid factor as a diagnostic marker in Rheumatiod arthritis2025
  5. 5Diagnostic utility and clinical relevance of anti-MCV and anti-CCP antibodies in rheumatoid arthritis2025