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July 1, 2025International Journal of Applied and Basic Medical Research

Evaluation of Diagnostic Efficacy of Anticyclic Citrullinated Peptide Antibody in Diagnosis of Rheumatoid Arthritis

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Authors

JSJagdeep SinghKGKapil GuptaNBNitin Bansal

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Overview

Evaluation reveals anti-CCP antibody's sensitivity of 97.7% in diagnosing rheumatoid arthritis, indicating its potential over traditional tests.

Key Points

  • Anti-CCP antibody shows a sensitivity of 97.7% in diagnosing rheumatoid arthritis, indicating its high detection potential.
  • The study evaluated 325 participants for diagnostic efficacy, comparing anti-CCP with traditional tests like ESR and CRP.
  • Findings suggest anti-CCP antibody can offer higher specificity at 75.77%, supporting its use for early diagnosis.
  • This study highlights the importance of anti-CCP in diagnosing RA, suggesting timely treatment may improve patient outcomes.

Cite This Study

Singh et al. (2025) studied this question.

synapsesocial.com/papers/68af3e49cf1dd9ea359eb633https://doi.org/10.4103/ijabmr.ijabmr_128_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Anti-cyclic citrullinated peptide antiboby and Rheumatoid factor as a diagnostic marker in Rheumatiod arthritis2025
  2. 2The Value of Rheumatoid Arthritis Citrullinated Peptides (<scp>RACP</scp>) System in the Diagnosis of Rheumatoid Arthritis: A Retrospective Analysis of 2632 Patients2025
  3. 3Diagnostic utility and clinical relevance of anti-MCV and anti-CCP antibodies in rheumatoid arthritis2025
  4. 4The Association of Anti-Cyclic Citrullinated Peptide Positivity with Extra-Articular Manifestations in Patients with Rheumatoid Arthritis2025 · 1 citations
  5. 5B-101 Performance assessment of a newly developed chemiluminescence assay for anti-CCP determination2025