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August 12, 2025Journal of Pediatric PsychologyOpen Access

Systematic review and meta-analysis of psychological interventions for depression symptoms in young people with long-term physical health conditions

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Authors

SPSarah E. D. PerzowJHJunxiao HuMBMadison Bristol

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Overview

Systematic review and meta-analysis find psychological interventions reduce depression symptoms in youth, suggesting they may provide essential support for this vulnerable group.

Key Points

  • Psychological interventions significantly reduce depression symptoms among young people with physical health conditions and may improve functional disability.
  • The pooled standardized mean differences for depression symptoms and functional disability were −0.30 and −0.35 respectively, both indicating significant effects.
  • This systematic review and meta-analysis included six randomized controlled trials featuring youth aged 11-18 years diagnosed with long-term health conditions.
  • Results highlight the need for further research to explore participant characteristics influencing the outcomes of psychological interventions.

Cite This Study

Perzow et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d64771527https://doi.org/10.1093/jpepsy/jsaf049
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