August 12, 2025International Journal of Reproductive BioMedicine (IJRM)Open Access

Comparison of clinical pregnancy rates between hormone replacement therapy and modified natural cycle for endometrial preparation in frozen embryo transfer cycles: An RCT

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Clinical pregnancy rates were similar in both the hormone replacement therapy and modified natural cycle groups.
No significant differences were found in secondary outcomes, such as implantation rate or early miscarriage between the two preparation methods.
Randomized clinical trial assessed 128 infertile women undergoing frozen embryo transfer in two distinct endometrial preparation approaches.
Results suggest that a modified natural cycle may be preferred due to fewer required monitoring visits and reduced hormonal intervention.

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Implication

Randomized clinical trial compares clinical pregnancy rates between hormone replacement therapy and modified natural cycle in frozen embryo transfer, suggesting similar outcomes.

Cite This Study

Safarloo et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d64771048 https://doi.org/10.18502/ijrm.v23i5.19264

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Implication

Randomized clinical trial compares clinical pregnancy rates between hormone replacement therapy and modified natural cycle in frozen embryo transfer, suggesting similar outcomes.

Comparison of clinical pregnancy rates between hormone replacement therapy and modified natural cycle for endometrial preparation in frozen embryo transfer cycles: An RCT

Key Points

Discussion

Implication

Cite This Study

Comparison of clinical pregnancy rates between hormone replacement therapy and modified natural cycle for endometrial preparation in frozen embryo transfer cycles: An RCT

Key Points

Discussion

Implication

Cite This Study

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