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September 5, 2025Gynecologic and Obstetric Investigation

Effects of different endometrial preparation protocols on pregnancy outcomes in women with polycystic ovarian syndrome undergoing frozen embryo transfer: A network meta-analysis

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Authors

MZMeiFang ZengHJHailing JiangBZBao–Ping Zhu

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Overview

Network meta-analysis reveals the effectiveness of various protocols on clinical pregnancy rates in PCOS, indicating potential miscarriage risks.

Key Points

  • The GnRH-a + HRT protocol significantly improves clinical pregnancy rates compared to HRT alone.
  • LE ovulation induction lowers miscarriage rates compared to hormone replacement therapy.
  • No significant differences in ongoing pregnancy rates were found among the studied protocols.
  • The network meta-analysis encompasses 16,082 frozen embryo transfer cycles from seventeen studies.

Cite This Study

Zeng et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d6477975bhttps://doi.org/10.1159/000547119
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