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August 22, 2025DiagnosticsOpen Access

Active Microbiological Surveillance for Contrasting Multi-Drug-Resistant Pathogens: Comparison Between a Multiplex Real-Time PCR Method and Culture

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Authors

GMGaetano MaugeriMCMaddalena CalvoGSGuido Scalia

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Overview

Molecular techniques improved detection of multidrug-resistant pathogens in rectal swabs, suggesting timely interventions.

Key Points

  • Molecular techniques achieved a high sensitivity of 100% in detecting multi-drug-resistant pathogens.
  • Out of 300 rectal swabs, 188 samples (62.6%) tested positive for at least one target using Allplex™ kits.
  • Observational analysis during the usual surveillance campaign highlighted the need for advanced diagnostic methods.
  • Combining molecular screening with culture can enhance detection rates in high-risk settings for antimicrobial resistance.

Cite This Study

Maugeri et al. (2025) studied this question.

synapsesocial.com/papers/68af76bf7567bf4f94feff56https://doi.org/10.3390/diagnostics15172128
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