August 23, 2025JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Plasminogen Activator Inhibitor-1 Levels in Heart Failure Patients: A Cross-sectional Study

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Authors

AKAmrit Pal KaurRoyal Manchester Children's Hospital JKJaskiran Kaur GMGurinder MohanAmrita Institute of Medical Sciences and Research Centre

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Implication

Cross-sectional study shows higher plasminogen activator inhibitor-1 levels in heart failure patients, indicating its potential as a diagnostic biomarker.

Key Points

Serum levels of plasminogen activator inhibitor-1 were significantly higher in heart failure patients than in healthy controls, suggesting its diagnostic potential.
In healthy individuals, the mean plasminogen activator inhibitor-1 level was 10.09 ng/mL, while in heart failure patients, it was 35.16 ng/mL, indicating a strong association.
A cross-sectional study included 100 participants, comparing groups of heart failure patients and healthy individuals for fibrinolysis biomarkers.
Identifying plasminogen activator inhibitor-1 levels may aid in early diagnosis of heart failure, but further research is essential for clinical applications.

Cite This Study

Kaur et al. (2025) studied this question.

synapsesocial.com/papers/68af76b97567bf4f94fefc6c https://doi.org/10.7860/jcdr/2025/75743.21431

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Implication

Cross-sectional study shows higher plasminogen activator inhibitor-1 levels in heart failure patients, indicating its potential as a diagnostic biomarker.

Plasminogen Activator Inhibitor-1 Levels in Heart Failure Patients: A Cross-sectional Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Plasminogen Activator Inhibitor-1 Levels in Heart Failure Patients: A Cross-sectional Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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