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August 23, 2025The Egyptian Journal of Internal MedicineOpen Access

Efficacy of paleolithic diet in control of blood glucose level in type 2 DM patients

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Authors

NSNagy Nageh Abdo SousMEManal El Sayed Ezz EldeenMEMohamed Elmasry

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Overview

Randomized trial improved glycemic control and lipid profiles in type 2 diabetes patients, indicating dietary changes may enhance treatment.

Key Points

  • Paleolithic Diet significantly reduced fasting glucose levels and HbA1c scores in type 2 diabetes patients after three months.
  • The intervention group showed improvements in insulin sensitivity measured by HOMA-IR compared to the control group at follow-up.
  • Cholesterol, triglycerides, and LDL levels decreased notably in those on the Paleolithic Diet, suggesting better lipid profiles.
  • Findings highlight the potential of dietary interventions in managing type 2 diabetes alongside standard therapies.

Cite This Study

Sous et al. (2025) studied this question.

synapsesocial.com/papers/68af76b97567bf4f94fefb90https://doi.org/10.1186/s43162-025-00453-6
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Paleo Nutritional Intervention for Type 2 Diabetes Mellitus: A Systematic Reevaluation and Consensus Report; Definition and Macronutrient Proposal for Trials2025
  2. 2Randomised crossover controlled trial of dietary interventions for glycaemic control when body weight is kept stable2025
  3. 3A review of interventional studies on plant-based diets for cardiometabolic outcomes in type 2 diabetes2025
  4. 4Effect of intermittent fasting, portfolio-moderate-carbohydrate, and anti-inflammatory diets on cardio-metabolic status in pre-diabetic patients; an open-label randomized clinical trial2025
  5. 5Diet Therapy Improves Body Composition, Blood Pressure and Glycemic Status in Individuals Living with Type 2 Diabetes: A Prospective Cohort Study2025