The effect of folic acid and B12 vitamin supplementation on mental well-being in pregnant women: A possible role in the prevention of postpartum depression

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Narrative review explores B-vitamin impact on maternal mental health and prevention of postpartum depression.

B-vitamin supplementation improves maternal mood and may reduce postpartum depression risk.
Low levels of folate and vitamin B12 linked to increased severity of depressive symptoms in mothers.
This narrative review evaluates evidence from clinical trials and observational studies from 1997 to May 2025.
Maternal mental health strategies could benefit from affordable B-vitamin supplementation.

Herian et al. (2025) studied this question.

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