August 22, 2025BMC PsychiatryOpen Access

Decomposing decision mechanisms in female substance use disorder: drift diffusion modeling of context-dependent biases in gain and loss processing

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The substance use disorder group showed a strong preference for immediate rewards, indicating impulsive behavior in gain scenarios.
Delay discounting analysis revealed significantly lower discount rates in the substance use disorder group during loss contexts.
Using drift diffusion modeling, the study assessed decision-making processes, identifying lower thresholds that reflect impulsivity.
Context-dependent decision biases were found to vary systematically with monetary and temporal parameters, highlighting the complexity of decision mechanisms.

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Analysis reveals context-dependent decision biases in female substance use disorder, suggesting unique cognitive processes at play.

Zhang et al. (2025) studied this question.

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