Macrophages drive a fibrogenic gene program of periductal fibroblasts in pediatric primary sclerosing cholangitis

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Detailing the immune response to TGFB2 in cholestatic liver disease of PSC patients and MDR2KO mice2025
2. 2Single-Cell RNA Sequencing Reveals Pericytes Acquire a Fibrotic Phenotype and Promote Mesenteric Adipose Tissue Fibrosis in Crohn's Disease.2025
3. 3A Conserved <scp>FABP5^high</scp> Macrophage Subset Promotes Fibrosis and Carcinogenesis in Advanced Liver Disease2025
4. 4Sex-Dependent Regulation of Liver Fibrosis in Primary Sclerosing Cholangitis: The Role of miR-125b, Androgen Receptors, TGF-β, and Apelin Signalling2025
5. 5Single-cell Transcriptome Analysis Reveals the Potential Role of Hepatic Stellate Cells in Liver Fibrosis2025